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Recombinant peptide replicates immunogenicity of synthetic linear peptide chimera for use as pre-erythrocytic stage malaria vaccine

Synthetic linear peptide chimeras (LPCs(cys+)) show promise as delivery platforms for malaria subunit vaccines. Maximal immune response to LPCs(cys+) in rodent malaria models depends upon formation of cross-linkages to generate homopolymers, presenting challenges for vaccine production. To replicate...

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Detalhes bibliográficos
Main Authors: Silva-Flannery, Luciana M., Cabrera-Mora, Monica, Jiang, Jianlin, Moreno, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673111/
https://ncbi.nlm.nih.gov/pubmed/19015042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2008.10.009
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