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Polyadenylation releases mRNA from RNA polymerase II in a process that is licensed by splicing
When transcription is coupled to pre-mRNA processing in HeLa nuclear extracts nascent transcripts become attached to RNA polymerase II during assembly of the cleavage/polyadenylation apparatus (CPA), and are not released even after cleavage at the poly(A) site. Here we show that these cleaved transc...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673064/ https://ncbi.nlm.nih.gov/pubmed/19304926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1409209 |
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