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Talampanel suppresses the acute and chronic effects of seizures in a rodent neonatal seizure model
PURPOSE: To test the efficacy of the novel candidate anticonvulsant talampanel (GYKI 53773) in a rodent model of hypoxic neonatal seizures. Talampanel is a noncompetitive antagonist of the alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid subtype of the glutamate receptor (AMPAR). We have pr...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672962/ https://ncbi.nlm.nih.gov/pubmed/19220413 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2008.01947.x |
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