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Construction and analysis of a modular model of caspase activation in apoptosis

BACKGROUND: A key physiological mechanism employed by multicellular organisms is apoptosis, or programmed cell death. Apoptosis is triggered by the activation of caspases in response to both extracellular (extrinsic) and intracellular (intrinsic) signals. The extrinsic and intrinsic pathways are cha...

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Autori principali: Harrington, Heather A, Ho, Kenneth L, Ghosh, Samik, Tung, KC
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672941/
https://ncbi.nlm.nih.gov/pubmed/19077196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4682-5-26
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