Pharmacological Preconditioning of Mesenchymal Stem Cells with Trimetazidine (1-[2,3,4-Trimethoxybenzyl]piperazine) Protects Hypoxic Cells against Oxidative Stress and Enhances Recovery of Myocardial Function in Infarcted Heart through Bcl-2 Expression

Stem cell transplantation is a possible therapeutic option to repair ischemic damage to the heart. However, it is faced with a number of challenges including the survival of the transplanted cells in the ischemic region. The present study was designed to use stem cells preconditioned with trimetazid...

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Detalhes bibliográficos
Main Authors: Wisel, Sheik, Khan, Mahmood, Kuppusamy, M. Lakshmi, Mohan, I. Krishna, Chacko, Simi M., Rivera, Brian K., Sun, Benjamin C., Hideg, Kálmán, Kuppusamy, Periannan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Pharmacology and Experimental Therapeutics 2009
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672865/
https://ncbi.nlm.nih.gov/pubmed/19218529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.150839
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