Study design considerations in a large COPD trial comparing effects of tiotropium with salmeterol on exacerbations

Currently available long-acting inhaled bronchodilators (tiotropium, salmeterol, formoterol) have demonstrated beneficial effects on exacerbations in placebo-controlled trials. However, there have been no direct comparisons of these drugs with exacerbations as the primary outcome and consequently CO...

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Detalhes bibliográficos
Main Authors: Beeh, Kai-Michael, Hederer, Bettina, Glaab, Thomas, Müller, Achim, Moelken, Maureen Rutten-van, Kesten, Steven, Vogelmeier, Claus
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2009
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672797/
https://ncbi.nlm.nih.gov/pubmed/19436693
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