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Structure and Substrate Recognition of the Escherichia coli DNA Adenine Methyltransferase
The structure of the Escherichia coli Dam DNA-(adenine-N6)-methyltransferase in complex with cognate DNA was determined at 1.89 Å resolution in the presence of S-adenosyl-l-homocysteine. DNA recognition and the dynamics of base-flipping were studied by site-directed mutagenesis, DNA methylation kine...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672621/ https://ncbi.nlm.nih.gov/pubmed/16524590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.02.028 |
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