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Abl Kinase Inhibits the Engulfment of Apopotic Cells in Caenorhabditis elegans

The engulfment of apoptotic cells is required for normal metazoan development and tissue remodeling. In Caenorhabditis elegans, two parallel and partially redundant conserved pathways act in cell-corpse engulfment. One pathway includes the adaptor protein CED-2 CrkII and the small GTPase CED-10 Rac,...

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Detalhes bibliográficos
Main Authors: Hurwitz, Michael E, Vanderzalm, Pamela J, Bloom, Laird, Goldman, Julia, Garriga, Gian, Horvitz, H. Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672617/
https://ncbi.nlm.nih.gov/pubmed/19402756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000099
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