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Structural Basis for Binding of RNA and Cofactor by a KsgA Methyltransferase
Among methyltransferases, KsgA and the reaction it catalyzes are conserved throughout evolution. However, the specifics of substrate recognition by the enzyme remain unknown. Here, we report structures of Aquifex aeolicus KsgA, in its ligand-free form, in complex with RNA and in complex with both RN...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2672589/ https://ncbi.nlm.nih.gov/pubmed/19278652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.01.010 |
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