Structural Basis for Binding of RNA and Cofactor by a KsgA Methyltransferase

Among methyltransferases, KsgA and the reaction it catalyzes are conserved throughout evolution. However, the specifics of substrate recognition by the enzyme remain unknown. Here, we report structures of Aquifex aeolicus KsgA, in its ligand-free form, in complex with RNA and in complex with both RN...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Tu, Chao, Tropea, Joseph E., Austin, Brian P., Court, Donald L., Waugh, David S., Ji, Xinhua
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672589/
https://ncbi.nlm.nih.gov/pubmed/19278652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.01.010
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky