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Mice lacking doublecortin and doublecortin-like kinase 2 display altered hippocampal neuronal maturation and spontaneous seizures

Mutations in doublecortin (DCX) are associated with intractable epilepsy in humans, due to a severe disorganization of the neocortex and hippocampus known as classical lissencephaly. However, the basis of the epilepsy in lissencephaly remains unclear. To address potential functional redundancy with...

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Bibliografische gegevens
Hoofdauteurs: Kerjan, Géraldine, Koizumi, Hiroyuki, Han, Edward B., Dubé, Celine M., Djakovic, Stevan N., Patrick, Gentry N., Baram, Tallie Z., Heinemann, Stephen F., Gleeson, Joseph G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672532/
https://ncbi.nlm.nih.gov/pubmed/19342486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812687106
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