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Transience of MHC Class I-restricted antigen presentation after influenza A virus infection

Antigen expressed as MHC Class I glycoprotein (pMHCI) complexes on dendritic cells is the primary driver of CD8(+) T cell clonal expansion and differentiation. As we seek to define the molecular differences between acutely stimulated cytotoxic T lymphocyte (CTL) effectors and long-lived memory T cel...

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Autori principali: Mintern, Justine D., Bedoui, Sammy, Davey, Gayle M., Moffat, Jessica M., Doherty, Peter C., Turner, Stephen J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672519/
https://ncbi.nlm.nih.gov/pubmed/19346476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901128106
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