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Reliabilities of identifying positive selection by the branch-site and the site-prediction methods

Natural selection operating in protein-coding genes is often studied by examining the ratio (ω) of the rates of nonsynonymous to synonymous nucleotide substitution. The branch-site method (BSM) based on a likelihood ratio test is one of such tests to detect positive selection for a predetermined bra...

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Detalhes bibliográficos
Main Authors: Nozawa, Masafumi, Suzuki, Yoshiyuki, Nei, Masatoshi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672471/
https://ncbi.nlm.nih.gov/pubmed/19339501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901855106
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