In Vivo Delta Opioid Receptor Internalization Controls Behavioral Effects of Agonists

BACKGROUND: GPCRs regulate a remarkable diversity of biological functions, and are thus often targeted for drug therapies. Stimulation of a GPCR by an extracellular ligand triggers receptor signaling via G proteins, and this process is highly regulated. Receptor activation is typically accompanied b...

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Главные авторы: Pradhan, Amynah A. A., Becker, Jérôme A. J., Scherrer, Grégory, Tryoen-Toth, Petra, Filliol, Dominique, Matifas, Audrey, Massotte, Dominique, Gavériaux-Ruff, Claire, Kieffer, Brigitte L.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672171/
https://ncbi.nlm.nih.gov/pubmed/19412545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005425
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