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Silencing Inhibits Cre-Mediated Recombination of the Z/AP and Z/EG Reporters in Adult Cells

BACKGROUND: The Cre-loxP system has been used to enable tissue specific activation, inactivation and mutation of many genes in vivo and has thereby greatly facilitated the genetic dissection of several cellular and developmental processes. In such studies, Cre-reporter strains, which carry a Cre-act...

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Detalhes bibliográficos
Main Authors: Long, Michael A., Rossi, Fabio M. V.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672169/
https://ncbi.nlm.nih.gov/pubmed/19415111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005435
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