Analysis of Genetic Variation in Akt2/PKB-β in Severe Insulin Resistance, Lipodystrophy, Type 2 Diabetes, and Related Metabolic Phenotypes

We previously reported a family in which a heterozygous missense mutation in Akt2 led to a dominantly inherited syndrome of insulin-resistant diabetes and partial lipodystrophy. To determine whether genetic variation in AKT2 plays a broader role in human metabolic disease, we sequenced the entire co...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Tan, Karen, Kimber, Wendy A., Luan, Jian’an, Soos, Maria A., Semple, Robert K., Wareham, Nicholas J., O’Rahilly, Stephen, Barroso, Inês
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672155/
https://ncbi.nlm.nih.gov/pubmed/17327441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db06-0921
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados