Convergent adaptation of human lactase persistence in Africa and Europe

A SNP in the gene encoding lactase (LCT) (C/T-13910) is associated with the ability to digest milk as adults (lactase persistence) in Europeans, but the genetic basis of lactase persistence in Africans was previously unknown. We conducted a genotype-phenotype association study in 470 Tanzanians, Ken...

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Auteurs principaux: Tishkoff, Sarah A, Reed, Floyd A, Ranciaro, Alessia, Voight, Benjamin F, Babbitt, Courtney C, Silverman, Jesse S, Powell, Kweli, Mortensen, Holly M, Hirbo, Jibril B, Osman, Maha, Ibrahim, Muntaser, Omar, Sabah A, Lema, Godfrey, Nyambo, Thomas B, Ghori, Jilur, Bumpstead, Suzannah, Pritchard, Jonathan K, Wray, Gregory A, Deloukas, Panos
Format: Artigo
Langue:Inglês
Publié: 2006
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672153/
https://ncbi.nlm.nih.gov/pubmed/17159977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1946
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