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Convergent adaptation of human lactase persistence in Africa and Europe

A SNP in the gene encoding lactase (LCT) (C/T-13910) is associated with the ability to digest milk as adults (lactase persistence) in Europeans, but the genetic basis of lactase persistence in Africans was previously unknown. We conducted a genotype-phenotype association study in 470 Tanzanians, Ken...

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Detalhes bibliográficos
Main Authors: Tishkoff, Sarah A, Reed, Floyd A, Ranciaro, Alessia, Voight, Benjamin F, Babbitt, Courtney C, Silverman, Jesse S, Powell, Kweli, Mortensen, Holly M, Hirbo, Jibril B, Osman, Maha, Ibrahim, Muntaser, Omar, Sabah A, Lema, Godfrey, Nyambo, Thomas B, Ghori, Jilur, Bumpstead, Suzannah, Pritchard, Jonathan K, Wray, Gregory A, Deloukas, Panos
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672153/
https://ncbi.nlm.nih.gov/pubmed/17159977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng1946
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