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Scoring mechanisms of p16(INK4a )immunohistochemistry based on either independent nucleic stain or mixed cytoplasmic with nucleic expression can significantly signal to distinguish between endocervical and endometrial adenocarcinomas in a tissue microarray study

BACKGROUND: Endocervical adenocarcinomas (ECAs) and endometrial adenocarcinomas (EMAs) are malignancies that affect uterus; however, their biological behaviors are quite different. This distinction has clinical significance, because the appropriate therapy may depend on the site of tumor origin. The...

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Detalhes bibliográficos
Main Authors: Koo, Chiew-Loon, Kok, Lai-Fong, Lee, Ming-Yung, Wu, Tina S, Cheng, Ya-Wen, Hsu, Jeng-Dong, Ruan, Alexandra, Chao, Kuan-Chong, Han, Chih-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672079/
https://ncbi.nlm.nih.gov/pubmed/19366452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-7-25
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