Mortality in human sepsis is associated with downregulation of Toll-like receptor 2 and CD14 expression on blood monocytes

Pattern recognition receptors are a key component of the first line host defense against infection, recognizing specific microbial products. We hypothesize that monocyte hyporesponsiveness in human sepsis is associated with a downregulation of the pattern recognition receptors Toll-like receptor (TL...

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Hlavní autoři: Schaaf, Bernhard, Luitjens, Karen, Goldmann, Torsten, van Bremen, Tobias, Sayk, Friedhelm, Dodt, Christoph, Dalhoff, Klaus, Droemann, Daniel
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672063/
https://ncbi.nlm.nih.gov/pubmed/19371402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1746-1596-4-12
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