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Homophilic and heterophilic polycystin 1 interactions regulate E-cadherin recruitment and junction assembly in MDCK cells

Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited human renal disease and is caused by mutations in two genes, PKD1 (85%) and PKD2 (15%). Cyst epithelial cells are characterised by a complex cellular phenotype including changes in proliferation, apoptosis, basement me...

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Detalhes bibliográficos
Main Authors: Streets, Andrew J., Wagner, Bart E., Harris, Peter C., Ward, Christopher J., Ong, Albert C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671929/
https://ncbi.nlm.nih.gov/pubmed/19351715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.045021
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