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γ-Aminobutyric Acid B Receptor Mediated Inhibition of Gonadotropin-Releasing Hormone Neurons Is Suppressed by Kisspeptin-G Protein-Coupled Receptor 54 Signaling

γ-Aminobutyric acid (GABA) is one of the most important neurotransmitters that regulate the excitability of GnRH neurons. Numerous studies have shown that GABA activates Cl(−) currents in GnRH neurons, and these effects are antagonized by GABA(A) receptor antagonists. The GABA(B) receptor is a heter...

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Detalhes bibliográficos
Main Authors: Zhang, Chunguang, Bosch, Martha A., Rønnekleiv, Oline K., Kelly, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671904/
https://ncbi.nlm.nih.gov/pubmed/19164470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1313
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