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Characterization of Relaxin Receptor (RXFP1) Desensitization and Internalization in Primary Human Decidual Cells and RXFP1-Transfected HEK293 Cells

We report here the desensitization and internalization of the relaxin receptor (RXFP1) after agonist activation in both primary human decidual cells and HEK293 cells stably transfected with RXFP1. The importance of β-arrestin 2 in these processes has also been demonstrated. Thus, in HEK-RXFP1 cells...

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Hlavní autoři: Kern, András, Bryant-Greenwood, Gillian D.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671891/
https://ncbi.nlm.nih.gov/pubmed/19116340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1385
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