Cancer-Stellate Cell Interactions Perpetuate the Hypoxia-Fibrosis Cycle in Pancreatic Ductal Adenocarcinoma

BACKGROUND AND AIMS: Although both cancer and stellate cells (PSCs) secrete proangiogenic factors, pancreatic cancer is a scirrhous and hypoxic tumor. The impact of cancer-PSCs interactions on angiogenesis was analyzed. METHODS: Expression of periostin, CD31, and α-smooth muscle actin was assessed b...

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Main Authors: Erkan, Mert, Reiser-Erkan, Carolin, Michalski, Christoph W, Deucker, Stefanie, Sauliunaite, Danguole, Streit, Sylvia, Esposito, Irene, Friess, Helmut, Kleeff, Jörg
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671860/
https://ncbi.nlm.nih.gov/pubmed/19412434
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