Inactivation of DltA Modulates Virulence Factor Expression in Streptococcus pyogenes

BACKGROUND: D-alanylated lipoteichoic acid is a virtually ubiquitous component of Gram-positive cell walls. Mutations in the dltABCD operon of numerous species exhibit pleiotropic effects, including reduced virulence, which has been attributed to increased binding of cationic antimicrobial peptides...

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Main Authors: Cox, Kathleen H., Ruiz-Bustos, Eduardo, Courtney, Harry S., Dale, James B., Pence, Morgan A., Nizet, Victor, Aziz, Ramy K., Gerling, Ivan, Price, Susan M., Hasty, David L.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671602/
https://ncbi.nlm.nih.gov/pubmed/19401780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005366
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