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Mathematical modeling of the formation of apoptosome in intrinsic pathway of apoptosis
Caspase-9 is the protease that mediates the intrinsic pathway of apoptosis, a type of cell death. Activation of caspase-9 is a multi-step process that requires dATP or ATP and involves at least two proteins, cytochrome c and Apaf-1. In this study, we mathematically model caspase-9 activation by usin...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2671592/ https://ncbi.nlm.nih.gov/pubmed/19333786 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11693-009-9022-y |
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