Identification of Human S100A9 as a Novel Target for Treatment of Autoimmune Disease via Binding to Quinoline-3-Carboxamides

Despite more than 25 years of research, the molecular targets of quinoline-3-carboxamides have been elusive although these compounds are currently in Phase II and III development for treatment of autoimmune/inflammatory diseases in humans. Using photoaffinity cross-linking of a radioactively labelle...

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Detalhes bibliográficos
Main Authors: Björk, Per, Björk, Anders, Vogl, Thomas, Stenström, Martin, Liberg, David, Olsson, Anders, Roth, Johannes, Ivars, Fredrik, Leanderson, Tomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671563/
https://ncbi.nlm.nih.gov/pubmed/19402754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000097
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