COP9-Associated CSN5 Regulates Exosomal Protein Deubiquitination and Sorting

Ubiquitinated endosomal proteins that are deposited into the lumens of multivesicular bodies are either sorted for lysosomal-mediated degradation or secreted as exosomes into the extracellular milieu. The mechanisms that underlie the sorting of cellular cargo proteins are currently unknown. In this...

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Detalhes bibliográficos
Main Authors: Liu, Yuelong, Shah, Spandan V., Xiang, Xiaoyu, Wang, Jianhua, Deng, Zhong-bin, Liu, Cunren, Zhang, Liming, Wu, Jianming, Edmonds, Tara, Jambor, Christina, Kappes, John C., Zhang, Huang-Ge
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671372/
https://ncbi.nlm.nih.gov/pubmed/19246649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080861
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