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Lymphotoxin-α and TNF Have Essential but Independent Roles in the Evolution of the Granulomatous Response in Experimental Leprosy

Recent studies identified an association between genetic variants in the lymphotoxin-α (LTα) gene and leprosy. To study the influence of LTα on the control of experimental leprosy, both low- and high-dose Mycobacterium leprae foot pad (FP) infections were evaluated in LTα-deficient chimeric (cLTα(−/...

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Detalhes bibliográficos
Main Authors: Hagge, Deanna A., Saunders, Bernadette M., Ebenezer, Gigi J., Ray, Nashone A., Marks, Vilma T., Britton, Warwick J., Krahenbuhl, James L., Adams, Linda B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671369/
https://ncbi.nlm.nih.gov/pubmed/19246648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080550
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