Trappin-2 Promotes Early Clearance of Pseudomonas aeruginosa through CD14-Dependent Macrophage Activation and Neutrophil Recruitment

Microaspiration of Pseudomonas aeruginosa contributes to the pathogenesis of nosocomial pneumonia. Trappin-2 is a host defense peptide that assists with the clearance of P. aeruginosa through undefined mechanisms. A model of macrophage interactions with replicating P. aeruginosa (strain PA01) in ser...

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Bibliographic Details
Main Authors: Wilkinson, Thomas S., Dhaliwal, Kevin, Hamilton, Thomas W., Lipka, Alexander F., Farrell, Lesley, Davidson, Donald J., Duffin, Rodger, Morris, Andrew Conway, Haslett, Chris, Govan, John R.W., Gregory, Christopher D., Sallenave, Jean-Michel, Simpson, A. John
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2009
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Regular Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671365/
https://ncbi.nlm.nih.gov/pubmed/19264904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080746
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