Characterization of a Hapten-Induced, Murine Model with Multiple Features of Atopic Dermatitis: Structural, Immunologic, and Biochemical Changes following Single Versus Multiple Oxazolone Challenges

Atopic dermatitis (AD) is a chronic dermatosis bearing clinical, histological, and immunologic similarities to chronic allergic contact dermatitis (ACD). AD shows a Th2 cell-dominant inflammatory infiltrate, elevated serum IgE levels, a permeability barrier abnormality, and Staphylococcus aureas col...

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Main Authors: Man, Mao-Qiang, Hatano, Yutaka, Lee, Seung H., Man, Mona, Chang, Sandra, Feingold, Kenneth R., Leung, Donald Y.M., Holleran, Walter, Uchida, Yoshikazu, Elias, Peter M.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671229/
https://ncbi.nlm.nih.gov/pubmed/17671515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.jid.5701011
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