A Conserved Multi-Gene Family Induces Cross-Reactive Antibodies Effective in Defense against Plasmodium falciparum

BACKGROUND: Two related merozoite surface proteins, MSP3 and MSP6, have previously been identified as targets of antibody-dependent cellular inhibition (ADCI), a protective mechanism against Plasmodium falciparum malaria. Both MSP3 and MSP6 share a common characteristic small N-terminal signature am...

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Detalhes bibliográficos
Main Authors: Singh, Subhash, Soe, Soe, Weisman, Simon, Barnwell, John W., Pérignon, Jean Louis, Druilhe, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671155/
https://ncbi.nlm.nih.gov/pubmed/19404387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005410
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