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Native display of complete foreign protein domains on the surface of hepatitis B virus capsids

The nucleocapsid of hepatitis B virus (HBV), or HBcAg, is a highly symmetric structure formed by multiple dimers of a single core protein that contains potent T helper epitopes in its 183-aa sequence. Both factors make HBcAg an unusually strong immunogen and an attractive candidate as a carrier for...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Kratz, Peter A., Böttcher, Bettina, Nassal, Michael
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1999
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26711/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10051569/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.5.1915
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