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High Glucose Suppresses Epidermal Growth Factor Receptor/Phosphatidylinositol 3-Kinase/Akt Signaling Pathway and Attenuates Corneal Epithelial Wound Healing

OBJECTIVE: Patients with diabetes are at an increased risk for developing corneal complications and delayed wound healing. This study investigated the effects of high glucose on epidermal growth factor receptor (EGFR) signaling and on epithelial wound healing in the cornea. RESEARCH DESIGN AND METHO...

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Detalhes bibliográficos
Main Authors: Xu, Ke-Ping, Li, Yanfeng, Ljubimov, Alexander V., Yu, Fu-Shin X.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671049/
https://ncbi.nlm.nih.gov/pubmed/19188434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-0997
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