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In vivo genetic mutations define predominant functions of the human T-cell leukemia/lymphoma virus p12(I) protein
The human T-cell leukemia/lymphoma virus type 1 (HTLV-1) ORF-I encodes a 99–amino acid hydrophobic membrane protein, p12(I), that affects receptors in different cellular compartments. We report here that proteolytic cleavage dictates different cellular localization and functions of p12(I). The remov...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670790/ https://ncbi.nlm.nih.gov/pubmed/18791162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-146928 |
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