Autocrine ATP release coupled to extracellular pyrophosphate accumulation in vascular smooth muscle cells

Extracellular inorganic pyrophosphate (PP(i)) is a potent suppressor of physiological calcification in bone and pathological calcification in blood vessels. Ectonucleotide pyrophosphatase/phosphodiesterases (eNPPs) generate PP(i) via the hydrolysis of ATP released into extracellular compartments by...

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Autori principali: Prosdocimo, Domenick A., Douglas, Dezmond C., Romani, Andrea M., O'Neill, W. Charles, Dubyak, George R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2009
Soggetti:
Vascular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670657/
https://ncbi.nlm.nih.gov/pubmed/19193865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00619.2008
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