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Abundance of the Na-K-2Cl cotransporter NKCC2 is increased by high-fat feeding in Fischer 344 X Brown Norway (F1) rats

Insulin resistance is associated with hypertension by mechanisms likely involving the kidney. To determine how the major apical sodium transporter of the thick ascending limb, the bumetanide-sensitive Na-K-2Cl cotransporter (NKCC2) is regulated by high-fat feeding, we treated young male, Fischer 344...

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Detalhes bibliográficos
Main Authors: Riazi, Shahla, Tiwari, Swasti, Sharma, Nikhil, Rash, Arjun, Ecelbarger, C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670636/
https://ncbi.nlm.nih.gov/pubmed/19193725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90484.2008
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