Protection by Anti-β-Glucan Antibodies Is Associated with Restricted β-1,3 Glucan Binding Specificity and Inhibition of Fungal Growth and Adherence

Anti-β-glucan antibodies elicited by a laminarin-conjugate vaccine confer cross-protection to mice challenged with major fungal pathogens such as Candida albicans, Aspergillus fumigatus and Cryptococcus neoformans. To gain insights into protective β-glucan epitope(s) and protection mechanisms, we st...

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Autors principals: Torosantucci, Antonella, Chiani, Paola, Bromuro, Carla, De Bernardis, Flavia, Palma, Angelina S., Liu, Yan, Mignogna, Giuseppina, Maras, Bruno, Colone, Marisa, Stringaro, Annarita, Zamboni, Silvia, Feizi, Ten, Cassone, Antonio
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670538/
https://ncbi.nlm.nih.gov/pubmed/19399183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005392
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