Wnt5a Exhibits Layer-Specific Expression in Adult Skin, Is Upregulated in Psoriasis, and Synergizes with Type 1 Interferon

BACKGROUND: Wnt5a is a member of the wingless-type patterning regulators important in pre-natal development. The expression and distribution of Wnt5a and its receptors frizzled (fzd) 3 and fzd 5 in adult human skin have not been comprehensively studied to date. METHODOLOGY/PRINCIPAL FINDINGS: We her...

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Detalhes bibliográficos
Main Authors: Romanowska, Malgorzata, Evans, Alan, Kellock, David, Bray, Susan E., McLean, Kathleen, Donandt, Susanne, Foerster, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670517/
https://ncbi.nlm.nih.gov/pubmed/19399181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005354
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