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Interfering with Glycolysis Causes Sir2-Dependent Hyper-Recombination of Saccharomyces cerevisiae Plasmids

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a key metabolic regulator implicated in a variety of cellular processes. It functions as a glycolytic enzyme, a protein kinase, and a metabolic switch under oxidative stress. Its enzymatic inactivation causes a major shift in the primary carbohydra...

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Detalhes bibliográficos
Main Authors: Ralser, Markus, Zeidler, Ute, Lehrach, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670500/
https://ncbi.nlm.nih.gov/pubmed/19390637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005376
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