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Identification of the Active Site in the Heparin II Domain of Fibronectin that Increases Outflow Facility in Cultured Monkey Anterior Segments

PURPOSE: To determine the active site in the Heparin II (HepII) domain of fibronectin that regulates outflow facility in cultured anterior segments and disrupts the actin cytoskeleton in transformed human trabecular meshwork (TM-1) cells. METHODS: Outflow facility was determined by two-level, consta...

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Bibliographic Details
Main Authors: Gonzalez, Jose M., Hu, Yujie, Gabelt, B’Ann T., Kaufman, Paul L., Peters, Donna M.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670490/
https://ncbi.nlm.nih.gov/pubmed/18757505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2143
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