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Protein Aggregation and Proteasome Dysfunction After Brain Ischemia

BACKGROUND AND PURPOSE: Protein unfolding and aggregation are dominant early pathogenic events in neurons after brain ischemia. This study used a transient cerebral ischemia model to investigate whether overproduction of unfolded proteins after brain ischemia is a consequence of proteasome dysfuncti...

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Main Authors: Ge, Pengfei, Luo, Yinan, Liu, Cindy L., Hu, Bingren
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670397/
https://ncbi.nlm.nih.gov/pubmed/17975104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.107.487108
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