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5′-Untranslated Region of the Tryptophan Hydroxylase-2 Gene Harbors an Asymmetric Bidirectional Promoter but not Internal Ribosome Entry Site in vitro

Tryptophan hydroxylase-2 (TPH2) catalyzes the synthesis of neuronal serotonin, a major neurotransmitter involved in many brain functions and psychiatric disorders. We have previously revealed a critical role of the human TPH2 (hTPH2) 5′-UTR in gene expression regulation. This study aimed to further...

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Detalhes bibliográficos
Main Authors: Chen, Guo-Lin, Miller, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670360/
https://ncbi.nlm.nih.gov/pubmed/19344641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2008.12.019
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