nhl-2 modulates microRNA activity in Caenorhabditis elegans

The C. elegans TRIM-NHL protein NHL-2 functions as a co-factor for the microRNA Induced Silencing Complex (miRISC) and thereby enhances the post-transcriptional repression of several genetically verified microRNA targets, including hbl-1 and let-60/Ras (by the let-7-family of microRNAs) and cog-1 (b...

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Bibliographic Details
Main Authors: Hammell, Christopher M., Lubin, Isabella, Boag, Peter R., Blackwell, T. Keith, Ambros, Victor
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670343/
https://ncbi.nlm.nih.gov/pubmed/19269369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.01.053
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