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Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma

BACKGROUND: HAND2, a key regulator for the development of the sympathetic nervous system, is located on chromosome 4q33 in a head-to-head orientation with DEIN, a recently identified novel gene with stage specific expression in primary neuroblastoma (NB). Both genes are expressed in primary NB as we...

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Detalhes bibliográficos
Main Authors: Voth, Harald, Oberthuer, André, Simon, Thorsten, Kahlert, Yvonne, Berthold, Frank, Fischer, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670301/
https://ncbi.nlm.nih.gov/pubmed/19348682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-10-28
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