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Loss of integrin α(v)β(8) on dendritic cells causes autoimmunity and colitis in mice
The cytokine transforming growth factor-β (TGF-β) is an important negative regulator of adaptive immunity1–3. TGF-β is secreted by cells as an inactive precursor that must be activated to exert biological effects4, but the mechanisms that regulate TGF-β activation and function in the immune system a...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670239/ https://ncbi.nlm.nih.gov/pubmed/17694047 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature06110 |
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