Unfractionated Heparin and New Heparin Analogues from Ascidians (Chordate-Tunicate) Ameliorate Colitis in Rats

The anti-inflammatory effect of mammalian heparin analogues, named dermatan sulfate and heparin, isolated from the ascidian Styela plicata was accessed in a TNBS-induced colitis model in rats. Subcutaneous administration of the invertebrate compounds during a 7-day period drastically reduced inflamm...

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Detalhes bibliográficos
Main Authors: Belmiro, Celso L. R., Castelo-Branco, Morgana T. L., Melim, Leandra M. C., Schanaider, Alberto, Elia, Celeste, Madi, Kalil, Pavão, Mauro S. G., de Souza, Heitor S. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670131/
https://ncbi.nlm.nih.gov/pubmed/19258310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807211200
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