SNAT2 Amino Acid Transporter Is Regulated by Amino Acids of the SLC6 γ-Aminobutyric Acid Transporter Subfamily in Neocortical Neurons and May Play No Role in Delivering Glutamine for Glutamatergic Transmission

System A transporters SNAT1 and SNAT2 mediate uptake of neutral α-amino acids (e.g. glutamine, alanine, and proline) and are expressed in central neurons. We tested the hypothesis that SNAT2 is required to support neurotransmitter glutamate synthesis by examining spontaneous excitatory activity afte...

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Detalhes bibliográficos
Main Authors: Grewal, Sukhjeevan, Defamie, Norah, Zhang, Xiong, De Gois, Stéphanie, Shawki, Ali, Mackenzie, Bryan, Chen, Chu, Varoqui, Hélène, Erickson, Jeffrey D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670127/
https://ncbi.nlm.nih.gov/pubmed/19240036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806470200
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