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Expression of Mcm2, geminin and Ki67 in normal oral mucosa, oral epithelial dysplasias and their corresponding squamous-cell carcinomas

Proteins necessary for the normal regulation of the cell cycle include minichromosome maintenance protein 2 (Mcm2) and geminin. These are overexpressed in several premalignant and malignant tumours. The Mcm2/Ki67 ratio can be used to estimate the population of cells that are in early G(1) (licensed...

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Detalhes bibliográficos
Main Authors: Torres-Rendon, A, Roy, S, Craig, G T, Speight, P M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669983/
https://ncbi.nlm.nih.gov/pubmed/19293805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604967
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