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Synaptic ionotropic glutamate receptors and plasticity are developmentally altered in the CA1 field of Fmr1 knockout mice

Fragile X syndrome is one of the most common forms of mental retardation, yet little is known about the physiological mechanisms causing the disease. In this study, we probed the ionotropic glutamate receptor content in synapses of hippocampal CA1 pyramidal neurons in a mouse model for fragile X (Fm...

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Autori principali: Pilpel, Yair, Kolleker, Aleksander, Berberich, Sven, Ginger, Melanie, Frick, Andreas, Mientjes, Edwin, Oostra, Ben A, Seeburg, Peter H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669971/
https://ncbi.nlm.nih.gov/pubmed/19103683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.160929
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