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Epistatic Module Detection for Case-Control Studies: A Bayesian Model with a Gibbs Sampling Strategy

The detection of epistatic interactive effects of multiple genetic variants on the susceptibility of human complex diseases is a great challenge in genome-wide association studies (GWAS). Although methods have been proposed to identify such interactions, the lack of an explicit definition of epistat...

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Detalhes bibliográficos
Main Authors: Tang, Wanwan, Wu, Xuebing, Jiang, Rui, Li, Yanda
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669883/
https://ncbi.nlm.nih.gov/pubmed/19412524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000464
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