Atg5 Regulates Phenethyl Isothiocyanate-induced Autophagic and Apoptotic Cell Death in Human Prostate Cancer Cells

Phenethyl isothiocyanate (PEITC) is a promising cancer chemopreventive agent but the mechanism of its anticancer effect is not fully understood. We now demonstrate, for the first time, that PEITC treatment triggers Atg5-dependent autophagic and apoptotic cell death in human prostate cancer cells. Ex...

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Hauptverfasser: Bommareddy, Ajay, Hahm, Eun-Ryeong, Xiao, Dong, Powolny, Anna A., Fisher, Alfred L., Jiang, Yu, Singh, Shivendra V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2669844/
https://ncbi.nlm.nih.gov/pubmed/19336571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4344
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